Two studies
were done using the two imidazoles derivatives; Itraconazole (Sporanox) and Ketoconazole
(Nizoral) for treatment of cutaneous leishmaniasis in Kuwait. According to the results of
our studies, together with the results of similar studies in the literature, we are now
treating cases of cutaneous leishmaniasis in our center according to the following protocol:
| 1- Few small lesions are treated with
liquid nitrogen. |
| 2- Few large lesions or multiple
lesions are treated with: |
| Itraconazole oral dose of 200 mg per day for a period of 6-8 weeks. |
|
In the past, we used Ketoconazole oral dose of 600 mg daily for a period of 6 weeks. |
| 3- Resistant lesions not responding to
the above treatments are given parentral sodium stibogluconate (Pentostam). |
Full-text articles demonstrating our
experience in our center with these two drugs:
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