PUVA For Mycosis Fungoids

72hrs-MPD

1. Initial dose: - 70% of MPD.
2. Increment: - If No erythema on normal skin -> Increase by 0.5-1.0 J/cm² /Week
3. No of Sittings: 2-3 sitting / week.

Follow up :- as for psoriasis.Continue ttt until cleared both clinically & histopathologically.

• Missed sittings:

- 1-2 missed sittings -> previous dose

- 3 missed sittings -> dose prior to last dose

- ³ 4 missed sittings -> 40% of last dose.

- ³ month -> repeat phototest.

• Adverse Effects:

- Mild erythema: same previous dose.

- Moderate erythema: same previous dose, next sitting -> Increase by 10% thereafter.

- Severe erythema: No ttt sitting (steroids, NSAIDs) & next sitting -> by 40% of last dose.

- Itch -> emollient plus antihistamine.

- Facial erythema -> sunscreen.

• Remarks:

-limit the use of topical steroids plus encourage frequent use of emollients.

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