PUVA For Psoriasis

72hrs-MPD

1. Initial dose: - 70% of MED.

2. Increment: - If No erythema on normal skin -> Increase 0.5-1.0 J/cm² /Week

3. No of Sittings: 3-4 sitting / week.

4. Followup: - ³ 80% improvement: -> Hold last dose.

- ³ 90% Maintenance: 4 ttt/w -> 2 ttt/2w -> 2 ttt/m

-Erythema during maintenance: -> Decrease dose by 25%.

- Relapse: -> Increase frequency of ttt.

• Missed sittings:

- 1-2 missed sittings: -> previous dose

- 3 missed sittings: -> dose prior to last dose

- ³ 4 missed sittings: -> 40% of last dose.

- ³ month: -> repeat phototest.

• Adverse Effects:

- Mild erythema: same previous dose.

- Moderate erythema: same previous dose, next sitting->Increase 10% thereafter.

- Severe erythema: No ttt sitting (steroids, NSAIDs) & repeat phototest.

- Itching: -> Emollient + Antihistamine.

- Facial erythema:-> Sunscreen.

• Remarks:

limit the use of topical steroids and encourage frequent use of emollient before treatment by applying a very thin layer of emollient.

Translate page on-line: French, German, Italian, Portuguese, Spanish

Back