Treatment Guidelines


PUVA For Mycosis Fungoids

72hrs-MPD

  1. Initial dose: - 70% of MPD.
  2. Increment: - If No erythema on normal skin -> Increase by 0.5-1.0 J/cm2 /Week
  3. No of Sittings: 2-3 sitting / week.
  4. Follow up :- as for psoriasis.Continue ttt until cleared both clinically & histopathologically.

  • Missed sittings:
  • - 1-2 missed sittings -> previous dose

    - 3 missed sittings -> dose prior to last dose

    - 4 missed sittings -> 40% of last dose.

    - month -> repeat phototest.

  • Adverse Effects:
  • - Mild erythema: same previous dose.

    - Moderate erythema: same previous dose, next sitting -> Increase by 10% thereafter.

    - Severe erythema: No ttt sitting (steroids, NSAIDs) & next sitting -> by 40% of last dose.

    - Itch -> emollient plus antihistamine.

    - Facial erythema -> sunscreen.

  • Remarks:
  • -limit the use of topical steroids plus encourage frequent use of emollients.

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